Professor Mel Calvert

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Professor Mel Calvert
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Role within SRMRC

Mel is a leading international expert in outcomes methodology and in particular, the use of patient reported outcomes in clinical trials and routine practice. She provides expert advice regarding the inclusion of patient reported outcomes in clinical trials carried out within the NIHR SRMRC

Other positions held

  • 2016 – present: Director Centre for Patient-Reported Outcomes Research
  • 2013- present: Professor of Outcomes Methodology
  • 2010 – present: NIHR West Midlands RDS Expert Advisor PROs/Trial Methodology

Qualifications

  • BSc Biochemistry (University of Birmingham)
  • PhD Biochemistry (University of Birmingham)

Based at

University of Birmingham

Biography

Melanie Calvert qualified with a BSc (First Class Hons) in Biochemistry from the University of Birmingham in 1997. She was awarded a Wellcome Trust Prize PhD studentship and graduated in 2001. Since then she has continued to work at the University with expertise in clinical trials, epidemiology, trials methodology and patient-reported outcomes.

Her work has included the development of the CONSORT-PRO extension published JAMA 2013 (cited over 500 times, to-date) for which she was awarded the ISOQOL Emerging Leader Award. More recent work includes publications on the conduct of PRO assessment within trials (PLOS One), issues surrounding ‘PRO Alerts’ (JAMA viewpoint, PLOS One), PROs in Big data (JRSM) and maximising the impact of patient reported outcome assessment for patients and society (BMJ). Professor Calvert has worked on a number of clinical trials, most notably the Cardiac REychronisation in Heart Failure Trial (which demonstrated significant improvements in symptoms, quality of life and survival in patients receiving CRT). More recently she has led the statistical analysis of the HINGE trial, published in Circulation, the HYPER Trial (Eur J Cardiothorac Surg) and the ROSSINI trial (BMJ).

In addition, Professor Calvert has led (as PI) a number of successful epidemiological studies assessing the management of diabetes and heart failure in primary care. Currently Professor Calvert is leading the development of a core outcome set within the NIHR funded PARTNERS2 programme grant, outcome selection/trials methodology within the NIHR funded Bluebelle, Pegasus, IMPRESS-AF and RATE-AF studies, the development of the SPIRIT-PRO extension (Lancet comment/funder Macmillan), ePRO development within routine practice (funded by Health Foundation/NIHR and charities) and an Innovate UK grant to assess patient reported outcomes in advanced therapies.

Contact details

0121 414 3354
m.calvert@bham.ac.uk

Professor Mel Calvert
LinkedIn
Other

0121 414 3354
m.calvert@bham.ac.uk

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