I am a laboratory-based experimental researcher and group leader in the fields of Biomaterials, Bioinspired engineering, Regenerative medicine, Stem cells, Biomimetic materials chemistry and Microfabrication (ion lithography, bioprinting, contact imprinting). Over the last 12 years, after leaving the Regenerative Medicine Group at the University of Southampton, I established five separate research teams from scratch in Bioinspired engineering across the Asia-Pacific region, and moved into technology translation while at the University of Hong Kong. The scope of my research ranges across regenerative ophthalmology, dentistry, orthopaedics and covers subjects such as, drug and gene delivery, proteomics, iPSC technology, nanotechnology, systems chemistry, regenerative protolife research, bioimaging, bioreactors, and biofabrication etc.
Dr DW Green is the lead experimental researcher on the NIHR-SRMRC project conceived and instituted by Dr Artemis Stamboulis to make a new class of antimicrobial biomaterials. In this research fellow position, I am making antimicrobial liquids for tissue engineering applications. The specific focus is on skin regeneration and orthopaedic healing after trauma. I am tasked with developing and synthesising of liquid biopolymers containing antimicrobial peptides derived from naturally occurring human defensins. AMPs are designed, synthesised and chemically bound to the polymer for the most effective functionality in the body. Our principle task is to print the polymers into 3D solid multi-material and multifunctional architectures into skin and bone equivalents, as well as tissue integrative coatings for implants. The bulk of the NIHR-SRMRC funded project is devoted to translation of the AMP liquid polymers into a translational clinical product. We are pursuing strategies for printing the liquids into self-supporting 3D anatomical gels, that can safely and effectively regenerate skin and bone tissues with significantly lower risks of infection that normally bedevil surgical implants. The materials work is carried out at Met & Mat. The biological evaluation, testing and validation is carried out with our NIHR partners at the Queen Elizabeth Hospital.
Other positions held
Visiting Professor, Guangzhou Medical University.
PhD. Biomimetic Medical Materials, University of Aston 2000.
School of Metallurgy & Materials, College of Engineering and Physicals Sciences, University of Birmingham.