Publications

2023

Anderson ED, Talukdar T, Goodwin G, Di Pietro V, Yakoub KM, Zwilling CE, Davies D, Belli A, Barbey AK. Assessing blood oxygen level-dependent signal variability as a biomarker of brain injury in sport-related concussion. Brain Commun. 2023 Aug 16;5(4):fcad215. doi: 10.1093/braincomms/fcad215. PMID: 37649639; PMCID: PMC10465085.

Xu Y, Malik N, Chernbumroong S, Vassallo J, Keene D, Foster M, Lord J, Belli A, Hodgetts T, Bowley D, Gkoutos G. Triage in major incidents: development and external validation of novel machine learning-derived primary and secondary triage tools. Emerg Med J. 2023 Sep 26:emermed-2022-212440. doi: 10.1136/emermed-2022-212440. Epub ahead of print. PMID: 37751994.

Horner E, Lord JM, Hazeldine J. The immune suppressive properties of damage associated molecular patterns in the setting of sterile traumatic injury. Front Immunol. 2023 Aug 15;14:1239683. doi: 10.3389/fimmu.2023.1239683. PMID: 37662933; PMCID: PMC10469493.

Courtie EF, Gilani A, Capewell N, Kale AU, Hui BTK, Liu X, Montesano G, Teussink M, Denniston AK, Veenith T, Blanch RJ. Reliability of Optical Coherence Tomography Angiography Retinal Blood Flow Analyses. Transl Vis Sci Technol. 2023 Jul 3;12(7):3. doi: 10.1167/tvst.12.7.3. PMID: 37395705; PMCID: PMC10324418

Hepschke JL, Laws E, Bin Saliman NH, Juncu S, Courtie E, Belli A, Blanch RJ. Modifications in Macular Perfusion and Neuronal Loss After Acute Traumatic Brain Injury. Invest Ophthalmol Vis Sci. 2023 Apr 3;64(4):35. doi: 10.1167/iovs.64.4.35. PMID: 37115535; PMCID: PMC10150830.

Price JMJ, Hisada Y, Hazeldine J, Bae-Jump V, Luther T, Mackman N, Harrison P. Detection of tissue factor-positive extracellular vesicles using the ExoView R100 system. Res Pract Thromb Haemost. 2023 May 16;7(4):100177. doi: 10.1016/j.rpth.2023.100177. PMID: 37333992; PMCID: PMC10276261.

Bentley C, Hazeldine J, Bravo L, Taylor AE, Gilligan LC, Shaheen F, Acharjee A, Gkoutos G, Foster MA, Arlt W, Lord JM. The ultra-acute steroid response to traumatic injury: a cohort study. Eur J Endocrinol. 2023 Mar 2;188(3):lvad024. doi: 10.1093/ejendo/lvad024. PMID: 36809311.

2022

Courtie E, Gilani A, Veenith T and Blanch RJ (2022) Optical coherence tomography angiography as a surrogate marker for end-organ resuscitation in sepsis: A review. Front. Med. 9:1023062. doi: 10.3389/fmed.2022.1023062

Green L, Brohi K, Allen E, Grant-Casey J, Doughty H, Estcourt L, Hearnshaw S, Klein A, Shanmugaranjan S, Phillips S, Hopkinson C. UK audit of the management of major bleeding and time taken to deliver blood products. Br J Anaesth. 2022 Nov;129(5):e111-e114. doi: 10.1016/j.bja.2022.07.036. Epub 2022 Aug 26. PMID: 36031419.

Disaster Preparedness. Heidi Doughty, Fateha Chowdhury and Richard Rackham. Practical Transfusion Medicine, Sixth Edition. Edited by Michael F. Murphy, David J. Roberts, Mark H. Yazer and Nancy M. Dunbar.© 2022 John Wiley & Sons Ltd. Published 2022 by John Wiley & Sons Ltd.

Cannon JW, Igra NM, Borge PD, Cap AP, Devine D, Doughty H et al. U.S. cities will not meet blood product resuscitation standards during major mass casualty incidents: Results of a THOR-AABB working party prospective analysis. Transfusion. 2022 Aug;62 Suppl 1:S12-S21. doi: 10.1111/trf.16960. Epub 2022 Jun 22. PMID: 35730720.

Jadhakhan F, Evans DW, Falla D. The role of post-trauma stress symptoms in the development of chronic musculoskeletal pain and disability: a systematic review. Eur J Pain. 2022 Nov 1. doi: 10.1002/ejp.2048. Epub ahead of print. PMID: 36317593.

Jadhakhan F, Evans D, Falla D. Early interventions for post-traumatic stress following musculoskeletal trauma: protocol for a systematic review and meta-analysis. BMJ Open. 2022 Sep 23;12(9):e065590. doi: 10.1136/bmjopen-2022-065590.

Toman E, Riley M, Hodgson S, Yakoub KM, Cooper L, Bishop J, Naumann DN, Welbury R, Hammond D, Di Pietro V, Belli A. Concussion in Non-athletes: Assessment of Cognition and Symptomatology (CONTACTS) study protocol – an exploratory cohort study investigating the utility of sports concussion assessment tools and salivary microRNAs to diagnose concussion in NHS patients. BMJ Open. 2022 Sep 21;12(9):e062030. doi: 10.1136/bmjopen-2022-062030. PMID: 36130754

Stevens AR, Hadis M, Milward M, Ahmed Z, Belli A, Palin W, Davies DJ. Photobiomodulation in Acute Traumatic Brain Injury: A Systematic Review and Meta-Analysis. J Neurotrauma. 2022 Aug 30. doi: 10.1089/neu.2022.0140.

Heyland DK, Wibbenmeyer L, Pollack JA, Friedman B, Turgeon AF, Eshraghi N et al.; RE-ENERGIZE Trial Team. A Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries. N Engl J Med. 2022 Sep 9. doi: 10.1056/NEJMoa2203364. Epub ahead of print. PMID: 36082909.

Acharjee A, Singh U, Choudhury SP, Gkoutos GV. The diagnostic potential and barriers of microbiome based therapeutics. Diagnosis (Berl). 2022 Aug 25. doi: 10.1515/dx-2022-0052. Epub ahead of print. PMID: 36000189

Evans DW, Rushton A, Middlebrook N, Bishop J, Barbero M, Patel J, Falla D. Estimating Risk of Chronic Pain and Disability Following Musculoskeletal Trauma in the United Kingdom. JAMA Netw Open. 2022 Aug 1;5(8):e2228870. doi: 10.1001/jamanetworkopen.2022.28870.

Bahcivanci B, Shafiha R, Gkoutos GV, Acharjee A. Associating transcriptomics data with inflammatory markers to understand tumour microenvironment in hepatocellular carcinoma. Cancer Med. 2022 Jun 18. doi: 10.1002/cam4.4941. Epub ahead of print. PMID: 35715992.

Irvine HJ, Acharjee A, Wolcott Z, Ament Z, Hinson HE, Molyneaux BJ, Simard JM, Sheth KN, Kimberly WT. Hypoxanthine is a pharmacodynamic marker of ischemic brain edema modified by glibenclamide. Cell Rep Med. 2022 Jun 21;3(6):100654. doi: 10.1016/j.xcrm.2022.100654. Epub 2022 Jun 13

Stevens AR, Stickland CA, Harris G, Ahmed Z, Goldberg Oppenheimer P, Belli A, Davies DJ. Raman Spectroscopy as a Neuromonitoring Tool in Traumatic Brain Injury: A Systematic Review and Clinical Perspectives. Cells. 2022 Apr 5;11(7):1227. doi: 10.3390/cells11071227

Cannon JW, Igra NM, Borge PD, Cap AP, Devine D, Doughty H, Geng Z, Guzman JF, Ness PM, Jenkins DH, Rajbhandary S, Schmulevich D, Stubbs JR, Wiebe DJ, Yazer MH, Spinella PC. U.S. cities will not meet blood product resuscitation standards during major mass casualty incidents: Results of a THOR-AABB working party prospective analysis. Transfusion. 2022 Jun 22. doi: 10.1111/trf.16960.

Stanworth SJ, Dowling K, Curry N, Doughty H, Hunt BJ, Fraser L, Narayan S, Smith J, Sullivan I, Green L; Transfusion Task Force of the British Society for Haematology. A guideline for the haematological management of major haemorrhage: a British Society for Haematology Guideline. Br J Haematol. 2022 Jun 10. doi: 10.1111/bjh.18275.

Low L, Suleiman K, Shamdas M, Bassilious K, Poonit N, Rossiter AE, Acharjee A, Loman N, Murray PI, Wallace GR, Rauz S. Gut Dysbiosis in Ocular Mucous Membrane Pemphigoid. Front Cell Infect Microbiol. 2022 Apr 14;12:780354. doi: 10.3389/fcimb.2022.780354.

Altarrah K, Tan P, Acharjee A, Hazeldine J, Torlinska B, Wilson Y, Torlinski T, Moiemen N, Lord JM. Differential benefits of steroid therapies in adults following major burn injury. J Plast Reconstr Aesthet Surg. 2022 Apr 20:S1748-6815(22)00193-0. doi: 10.1016/j.bjps.2022.04.007.

Bazaie N., Alghamdi I., Alqurashi N., Ahmed Z. (2022). The Impact of a Cervical Collar on Intracranial Pressure in Traumatic Brain Injury Patients: A Systematic Review and Meta-Analysis. Trauma Care 2: 1-10.

Humphries R., Naumann D.N., Ahmed Z. (2022). Use of Haemostatic Devices for the Control of Junctional and Abdominal Traumatic Haemorrhage: A Systematic Review. Trauma Care 2: 23-38.

Xu Y, Nash K, Acharjee A, Gkoutos GV. CACONET: a novel classification framework for microbial correlation networks. Bioinformatics. 2022 Jan 4 doi: 10.1093/bioinformatics/btab879. PMID: 34983063.

Doughty HA, Hervig TA. Whole blood for transfusion in sub-Saharan Africa. Lancet Glob Health. 2022 Mar;10(3):e303-e304. doi: 10.1016/S2214-109X(22)00033-X. PMID: 35180402.

Smith H, Doughty H. Training trial of critical care paramedics for non-medical authorisation of blood. Br Paramed J. 2022 Mar 1;6(4):55-59. doi: 10.29045/14784726.2022.03.6.4.55. PMID: 35330861.

2021

Couch Y, Buzàs EI, Vizio DD, Gho YS, Harrison P, Hill AF. A brief history of nearly EV-erything – The rise and rise of extracellular vesicles. J Extracell Vesicles. 2021 Dec;10(14):e12144. doi: 10.1002/jev2.12144. PMID: 34919343

Large J, Naumann DN, Fellows J, Connor C, Ahmed Z. Clinical outcomes following major trauma for patients with a diagnosis of depression: a large UK database analysis. Trauma Surg Acute Care Open. 2021 Dec 14;6(1):e000819. doi: 10.1136/tsaco-2021-000819. PMID: 34966855

Acharjee A, Gribaleva E, Bano S, Gkoutos GV. Multi-omics-based identification of atopic dermatitis target genes and their potential associations with metabolites and miRNAs. Am J Transl Res. 2021 Dec 15;13(12):13697-13709. PMID: 35035708

Doughty H, Green L. Transfusion support during mass casualty events. Br J Anaesth. 2022 Feb;128(2) doi: 10.1016/j.bja.2021.07.027. PMID: 34503826.

Acharjee A, Hazeldine J, Bazarova A, Deenadayalu L, Zhang J, Bentley C. Integration of Metabolomic and Clinical Data Improves the Prediction of Intensive Care Unit Length of Stay Following Major Traumatic Injury. Metabolites. 2021 Dec 31;12(1):29. doi: 10.3390/metabo12010029. PMID: 35050151.

Hashmi Y, Ayyaz N, Umar H, Jawaid A, Ahmed Z. Are Trauma Surgery Simulation Courses Beneficial in Low- and Middle-Income Countries—A Systematic Review and Meta-Analysis. Trauma Care 2021 http://dx.doi.org/10.3390/traumacare1030012

Khan S., Ali A.S., Kadir B., Ahmed Z., Di Pietro V. (2021). Effects of memantine in patients with traumatic brain injury: a systematic review. Trauma Care 1: 1-14. https://doi.org/10.3390/traumas1010001

Alhenaki A.M., Ali A.S., Kadir B., Ahmed Z. (2021). Prehospital administration of tranexamic acid in trauma patients: A systematic review and meta-analysis. Trauma, https://doi.org/10.1177/14604086211001163.

Vassallo J, Chernbumroong S, Malik N, Xu Y, Keene D, Gkoutos G, Lyttle MD, Smith J; in collaboration with PERUKI (Paediatric Emergency Research in the UK and Ireland). Comparative analysis of major incident triage tools in children: a UK population-based analysis. Emerg Med J. 2021 doi: 10.1136/emermed-2021-211706. Epub ahead of print. PMID: 34706900.

Jadhakhan F, Evans D, Falla D. Role of post-trauma stress symptoms in the development of chronic musculoskeletal pain and disability: a protocol for a systematic review. BMJ Open. 2021 doi: 10.1136/bmjopen-2021-058386. PMID: 34853117.

Shafiha R, Bahcivanci B, Gkoutos GV, Acharjee A. Machine Learning-Based Identification of Potentially Novel Non-Alcoholic Fatty Liver Disease Biomarkers. Biomedicines. 2021 doi: 10.3390/biomedicines9111636. PMID: 34829865

Tollman J, Ahmed Z. Efficacy of tracheal tube introducers and stylets for endotracheal intubation in the prehospital setting: a systematic review and meta-analysis. Eur J Trauma Emerg Surg. 2021 doi: 10.1007/s00068-021-01762-5. Epub ahead of print. PMID: 34333690.

Osgood C, Ahmed Z, Di Pietro V. Co-Expression Network Analysis of MicroRNAs and Proteins in Severe Traumatic Brain Injury: A Systematic Review. Cells. 2021 doi: 10.3390/cells10092425. PMID: 34572074

Masterman E, Ahmed Z. Experimental Treatments for Oedema in Spinal Cord Injury: A Systematic Review and Meta-Analysis. Cells. 2021 doi: 10.3390/cells10102682. PMID: 34685662

Kearney RS, Ji C, Warwick J, Parsons N, Brown J, Harrison P, Young J, Costa ML; ATM Trial Collaborators. Effect of Platelet-Rich Plasma Injection vs Sham Injection on Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy: A Randomized Clinical Trial. JAMA. 2021 13;326(2):137-144. doi: 10.1001/jama.2021.6986. PMID: 34255009; PMCID: PMC8278266

Hughes, E.A.B., Robinson, T.E., Moakes, R.J.A. et al. Controlled self-assembly of chemical gardens enables fabrication of heterogeneous chemobrionic materials. Commun Chem 4, 145 (2021). https://doi.org/10.1038/s42004-021-00579-y

Koppad S, B A, Gkoutos GV, Acharjee A. Cloud Computing Enabled Big Multi-Omics Data Analytics. Bioinform Biol Insights. 2021 Jul doi: 10.1177/11779322211035921. PMID: 34376975; PMCID: PMC8323418.

Iacucci M, Jeffery L, Acharjee A, Nardone OM, Zardo D, Smith SCL, Bazarova A, Cannatelli R, Shivaji UN, Williams J, Gkoutos GV, Ghosh S, Ultra-High Magnification Endocytoscopy and Molecular Markers for Defining Endoscopic AND Histologic Remission In Ulcerative Colitis – An exploratory Pilot Study in search of defining Deep Remission; Inflammatory Bowel Disease 2021 27(11):1719-1730 doi: 10.1093/ibd/izab059

Malik NS, Chernbumroong S, Xu Y, Vassallo J, Lee J, Moran CG et al. Paediatric major incident triage: UK military tool offers best performance in predicting the need for time-critical major surgical and resuscitative intervention. EClinicalMedicine Published online first August 23, 2021. DOI: https://doi.org/10.1016/j.eclinm.2021.101100

Green DW et al. Synthetic tissue engineering with smart, cytomimetic protocells. Biomaterials. 2021;276:120941. doi:10.1016/j.biomaterials.2021.120941. PMID: 34298445.

Courtie EF, Kale AU, Hui BTK, Liu X, Capewell NI, Bishop JRB, Whitehouse T, Veenith T, Logan A, Denniston AK, Blanch RJ. Stability of OCT and OCTA in the Intensive Therapy Unit Setting. Diagnostics (Basel). 2021;11(8):1516. doi: 10.3390/diagnostics11081516. PMID: 34441449; PMCID: PMC8394026

Hazeldine J, McGee KC, Al-Tarrah K, Hassouna T, Patel K, Imran R, Bishop JRB, Bamford A, Barnes D, Wilson Y, Harrison P, Lord JM, Moiemen NS. Multicentre, longitudinal, observational cohort study to examine the relationship between neutrophil function and sepsis in adults and children with severe thermal injuries: a protocol for the Scientific Investigation of the Biological Pathways Following Thermal Injury-2 (SIFTI-2) study. BMJ Open. 2021 Oct 22;11(10):e052035. doi: 10.1136/bmjopen-2021-052035. PMID: 34686556.

Cato LD, Bailiff B, Price J, Ermogeneous C, Hazeldine J, Lester W, Lowe G, Wearn C, Bishop JRB, Lord JM, Moiemen N, Harrison P. Heparin resistance in severe thermal injury: A prospective cohort study. Burns Trauma. 2021. doi: 10.1093/burnst/tkab032. PMID: 34692855; PMCID: PMC8528639.

Begum G, Leigh T, Stanley D, Logan A, Blanch RJ. Determining the effect of ocular chemical injuries on topical drug delivery. Drug Deliv. 2021;28(1):2044-2050. doi: 10.1080/10717544.2021.1979124. PMID: 34595979.

Saliman NH, Belli A, Blanch RJ. Afferent Visual Manifestations of Traumatic Brain Injury. J Neurotrauma. 2021. doi: 10.1089/neu.2021.0182. Epub ahead of print. PMID: 34269619.

Bentley C, Potter C, Yakoub KM, et al. A prospective, phase II, single-centre, cross-sectional, randomised study investigating Dehydroepiandrosterone supplementation and its Profile in Trauma: ADaPT. BMJ Open 2021;11:e040823. doi: 10.1136/bmjopen-2020-040823 PMID: 34312190 PMCID: PMC8314713

Bates M, Watts S, Doughty H, Woolley T, Miles A, Barry L, Jenner D, Sedman A, Purcell R, Kirkman E. Effect of parachute delivery on red blood cell (RBC) and plasma quality measures of blood for transfusion. Transfusion. 2021 Jul;61 Suppl 1:S223-S233. doi: 10.1111/trf.16501. PMID: 34269457.

Price J, Gardiner C, Harrison P. Platelet-enhanced plasma: Characterization of a novel candidate resuscitation fluid’s extracellular vesicle content, clotting parameters, and thrombin generation capacity. Transfusion. 2021 May 4. doi: 10.1111/trf.16423. Epub ahead of print. PMID: 33948950.

Iacucci M, Jeffery L, Acharjee A, Nardone OM, Zardo D, Smith SCL, Bazarova A, Cannatelli R, Shivaji UN, Williams J, Gkoutos G, Ghosh S. Ultra-high Magnification Endocytoscopy and Molecular Markers for Defining Endoscopic and Histologic Remission in Ulcerative Colitis-An Exploratory Study to Define Deep Remission. Inflamm Bowel Dis. 2021 May 21:izab059. doi: 10.1093/ibd/izab059. Epub ahead of print. PMID: 34019073

Smith H, Doughty H, Bishop J, Herbert M, Nash M. Temperature mapping in an air ambulance helicopter: Implications for the delivery of pre-hospital transfusion. Transfusion. 2021 Jul;61 Suppl 1:S206-S213. doi: 10.1111/trf.16517. PMID: 34269452

Bisht V, Acharjee A, Gkoutos GV. NFnetFu: A novel workflow for microbiome data fusion. Comput Biol Med. 2021 Jun 8;135:104556. doi: 10.1016/j.compbiomed.2021.104556. Epub ahead of print. PMID: 34216888.

Hazeldine J, Lord JM. Neutrophils and COVID-19: Active Participants and Rational Therapeutic Targets. Front Immunol. 2021 Jun 2;12:680134. doi: 10.3389/fimmu.2021.680134. PMID: 34149717; PMCID: PMC8206563

Malik NS, Chernbumroong S, Xu Y, Vassallo J, Lee J, Bowley DM et al. The BCD Triage Sieve outperforms all existing major incident triage tools: Comparative analysis using the UK national trauma registry population. eClinicalMedicine. Vol 36, 100888, June 01, 2021. Published online first May 14, 2021. DOI: https://doi.org/10.1016/j.eclinm.2021.100888

Marsden MER, Vulliamy PED, Carden R, Naumann DN, Davenport RA; National Trauma Research and Innovation Collaborative (NaTRIC). Trauma Laparotomy in the UK: A Prospective National Service Evaluation. J Am Coll Surg. 2021:S1072-7515(21)00361-6. doi: 10.1016/j.jamcollsurg.2021.04.031. Epub ahead of print. PMID: 34015456

Price K, Moiemen N, Nice L, Mathers J. Patient experience of scar assessment and the use of scar assessment tools during burns rehabilitation: a qualitative study, Burns & Trauma, Volume 9, 2021, tkab005, https://doi.org/10.1093/burnst/tkab005

Turner GM, McMullan C, Aiyegbusi OL, Bem D, Marshall T, Calvert M et al. Stroke risk following traumatic brain injury: Systematic review and meta-analysis. Int J Stroke. 2021 Apr 4:17474930211004277. doi: 10.1177/17474930211004277. Epub ahead of print. PMID: 33705244.

Hazeldine J, Dinsdale RJ, Naumann DN, Acharjee A, Bishop JRB, Lord JM et al. Traumatic injury is associated with reduced deoxyribonuclease activity and dysregulation of the actin scavenging system. Burns & Trauma, Volume 9, 2021, tkab001 doi: 10.1093/burnst/tkab001. eCollection 2021 Jan

Di Pietro V, O’Halloran P, Watson CN, Begum G, Acharjee A, Yakoub KM et al. Unique diagnostic signatures of concussion in the saliva of male athletes: the Study of Concussion in Rugby Union through MicroRNAs (SCRUM). Br J Sports Med. Published Online First: 23 March 2021. doi: 10.1136/bjsports-2020-103274

Hall TJ, Hughes EAB, Sajjad H, Kuehne SA, Grant MM, Grover LM et al. Formulation of a reactive oxygen producing calcium sulphate cement as an anti-bacterial hard tissue scaffold. Sci Rep. 2021 Feb 24;11(1):4491. doi: 10.1038/s41598-021-84060-9. PMID: 33627825; PMCID: PMC7904759

Wood H, Acharjee A, Pearce H, Quraishi MN, Powell R, Rossiter A, Beggs A, Ewer A, Moss P, Toldi G. Breastfeeding promotes early neonatal regulatory T-cell expansion and immune tolerance of non-inherited maternal antigens. Allergy. 2021 Jan 12. doi: 10.1111/all.14736. Epub ahead of print. PMID: 33432577.

Koch M, Acharjee A, Ament Z, Schleicher R, Bevers M, Stapleton C, Patel A, Kimberly WT. Machine Learning-Driven Metabolomic Evaluation of Cerebrospinal Fluid: Insights Into Poor Outcomes After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery. 2021 Jan 19:nyaa557. doi: 10.1093/neuros/nyaa557. Epub ahead of print. PMID: 33469656.

Lall R, Mistry D, Skilton E, Boota N, Regan S, Bion J et al. Study into the reversal of septic shock with landiolol (beta blockade): STRESS-L Study protocol for a randomised trial. BMJ Open. 2021 Feb 16;11(2):e043194. doi: 10.1136/bmjopen-2020-043194. PMID: 33593781.

Hughes EAB, Jones-Salkey O, Forey P, Chipara M, and Grover LM. Exploring the formation of calcium orthophosphatepyrophosphate chemical gardens. ChemSystemsChem 10.1002/syst.202000062

Khan S, Ali AS, Kadir B, Ahmed Z, Di Pietro V. Effects of Memantine in Patients with Traumatic Brain Injury: A Systematic Review. Traumas 2021, 1, 1–14.https://doi.org/10.3390/traumas 1010001

Middlebrook N, Rushton AB, Abichandani D, Kuithan P, Heneghan NR, Falla D. Measures of central sensitization and their measurement properties in musculoskeletal trauma: A systematic review. Eur J Pain. 2021 Jan;25(1):71-87. doi: 10.1002/ejp.1670. Epub 2020 Oct 27. PMID: 33034137.

2020

Hutchinson PJ, Edlmann E, Bulters D, Zolnourian A, Holton P, Suttner N et al. Trial of Dexamethasone for Chronic Subdural Hematoma. N Engl J Med. 2020 Dec 16. doi: 10.1056/NEJMoa2020473. Epub ahead of print. PMID: 33326713

Hawkridge K, Ahmed I, Ahmed Z. Evidence for the use of spinal collars in stabilising spinal injuries in the pre-hospital setting in trauma patients: a systematic review. Eur J Trauma Emerg Surg. 2020 Dec 21. doi: 10.1007/s00068-020-01576-x. Epub ahead of print. PMID: 33346863

Courtie E, Veenith T, Logan A, Denniston AK, Blanch RJ. Retinal blood flow in critical illness and systemic disease: a review. Ann Intensive Care. 2020 Nov 12;10(1):152. doi: 10.1186/s13613-020-00768-3. PMID: 33184724; PMCID: PMC7661622

Cox LS, Bellantuono I, Lord JM, Sapey E, Mannick J, Partridge L, Gordon AL, Steves CJ, Witham MD. Tackling immunosenescence to improve COVID-19 outcomes and vaccine response in older adults. Lancet Healthy Longevity. 2020;1 (2): E55-E57

Acharjee A, Larkman J, Xu Y, Cardoso VR, Gkoutos GV. A random forest based biomarker discovery and power analysis framework for diagnostics research. BMC Med Genomics. 2020 Nov 23;13(1):178. doi: 10.1186/s12920-020-00826-6. PMID: 33228632; PMCID: PMC7685541

Hazeldine J, Lord JM. Immunesenescence: A Predisposing Risk Factor for the Development of COVID-19? Front Immunol. 2020 Oct 6;11:573662. doi: 10.3389/fimmu.2020.573662. PMID: 33123152; PMCID: PMC7573102

Aziz F, Acharjee A, Williams JA, Russ D, Bravo-Merodio L, Gkoutos GV. Biomarker Prioritisation and Power Estimation Using Ensemble Gene Regulatory Network Inference. Int J Mol Sci. 2020 Oct 23;21(21):E7886. doi: 10.3390/ijms21217886. PMID: 33114263

Liu X, Cruz Rivera S, Moher D, Calvert MJ, Denniston AK; SPIRIT-AI and CONSORT-AI Working Group. Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension. Nat Med. 2020 Sep;26(9):1364-1374. doi: 10.1038/s41591-020-1034-x. Epub 2020 Sep 9. PMID: 32908283

Cruz Rivera S, Liu X, Chan AW, Denniston AK, Calvert MJ; SPIRIT-AI and CONSORT-AI Working Group; SPIRIT-AI and CONSORT-AI Steering Group; SPIRIT-AI and CONSORT-AI Consensus Group. Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension. Nat Med. 2020 Sep;26(9):1351-1363. doi: 10.1038/s41591-020-1037-7. Epub 2020 Sep 9. PMID: 32908284.

Ament Z, Bevers MB, Wolcott Z, Kimberly WT, Acharjee A. Uric Acid and Gluconic Acid as Predictors of Hyperglycemia and Cytotoxic Injury after Stroke. Transl Stroke Res. 2020 Oct 17. doi: 10.1007/s12975-020-00862-5. Epub ahead of print. PMID: 33067777.

Begum G, Leigh T, Courtie E, Moakes R, Butt G, Ahmed Z et al. Rapid assessment of ocular drug delivery in a novel ex vivo corneal model. Sci Rep. 2020 Jul 16;10(1):11754. doi: 10.1038/s41598-020-68254-1. PMID: 32678110; PMCID: PMC7366725

Forcione M, Chiarelli AM, Davies DJ, Perpetuini D, Sawosz P, Merla A, Belli A. Cerebral perfusion and blood-brain barrier assessment in brain trauma using contrast-enhanced near-infrared spectroscopy with indocyanine green: A review. J Cereb Blood Flow Metab. 2020 Aug;40(8):1586-1598. doi: 10.1177/0271678X20921973. Epub 2020 Apr 28. PMID: 32345103; PMCID: PMC7370372

Robinson TE, Eisenstein NM, Cox SC, Moakes RJA, Thompson AM, Ahmed Z et al. Local injection of a hexametaphosphate formulation reduces heterotopic ossification in vivo. Mater Today Bio. 2020 Jun 2;7:100059. doi: 10.1016/j.mtbio.2020.100059. PMID: 32613185; PMCID: PMC7322360

Bentley C, Cooper L, Foster M, Fallowfield J. Reflecting on success in trauma research: experiences from the SGCNS and SIR studies [published online ahead of print, 2020 Jun 2]. BMJ Mil Health. 2020;bmjmilitary-2020-001467. doi:10.1136/bmjmilitary-2020-001467

Middlebrook N, Heneghan NR, Evans DW, Rushton A, Falla D. Reliability of temporal summation, thermal and pressure pain thresholds in a healthy cohort and musculoskeletal trauma population. PLoS One. 2020;15(5):e0233521. Published 2020 May 29. doi:10.1371/journal.pone.0233521

Chimen M, Evryviadou A, Box CL, Harrison MJ, Hazeldine J, Dib LH et al. Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation. Haematologica. 2020;105(5):1248‐1261. doi:10.3324/haematol.2018.215145

Hughes EA, Chipara M, Hall TJ, Williams RL, Grover LM. Chemobrionic structures in tissue engineering: self-assembling calcium phosphate tubes as cellular scaffolds. Biomater Sci. 2019 Dec 12. doi: 10.1039/c9bm01010f.

Bravo-Merodio L, Acharjee A, Hazeldine J, Bentley C, Foster M, Gkoutos GV, et al. Machine learning for the detection of early immunological markers as predictors of multi-organ dysfunction. Sci Data 6, 328 2019 Dec. doi.org/10.1038/s41597-019-0337-6

Rickard J.J.S, Di-Pietro, V, Smith D.J, Belli A, Goldberg Oppenheimer P. Rapid optofluidic detection of biomarkers for traumatic brain injury via surface-enhanced Raman spectroscopy. Nat Biomed Eng (2020). doi.org/10.1038/s41551-019-0510-4

Begum G. Reddy R. Yakoub K.M. Belli A. Davies D.J, Di Pietro V. Differential Expression of Circulating Inflammatory Proteins Following Sport-Related Traumatic Brain Injury. Int. J. Mol. Sci. 2020, 21, 1216. https://doi.org/10.3390/ijms21041216

Mahmood A, Needham K, Shakur-Still H. et al. Tranexamic acid in traumatic brain injury: an explanatory study nested within the CRASH-3 trial. Eur J Trauma Emerg Surg 2020 Feb. doi.org/10.1007/s00068-020-01316-1

Chaudhary R, Scott R, Wallace G, Berry M, Logan A, Blanch R. Inflammatory and Fibrogenic Factors In Proliferative Vitreoretinopathy Development. Translational Vision Science & Technology 2020 Feb, Vol.9, 23. doi:https://doi.org/10.1167/tvst.9.3.23

Quraishi MN, Acharjee A, Beggs AD, Horniblow R, Tselepis C, Gkoutos G, et al. A pilot integrative analysis of colonic gene expression, gut microbiota and immune infiltration in primary sclerosing cholangitis-inflammatory bowel disease: association of disease with bile acid pathways. J Crohns Colitis. 2020 Feb 4. pii: jjaa021. doi: 10.1093/ecco-jcc/jjaa021

Di Pietro V, Yakoub KM, Caruso G, Lazzarino G, Signoretti S, Barbey AK, et al. Antioxidant Therapies in Traumatic Brain Injury. Antioxidants. 2020 Feb; 9(3):260. doi: 10.3390/antiox9030260

Foster MA, Taylor AE, Hill NE, Bentley C, Bishop J, Gilligan LC, Shaheen F, et al. Mapping the Steroid Response to Major Trauma From Injury to Recovery: A Prospective Cohort Study. J Clin Endocrinol Metab. 2020 Mar 1;105(3). pii: dgz302. doi: 10.1210/clinem/dgz302.

Malik NS, Munoz B, de Courcey C, Imran R, Lee KC, Chernbumroong S, et al. Violence-related knife injuries in a UK city; epidemiology and impact on secondary care resources. EClinicalMedicine. 2020 Mar https://doi.org/10.1016/j.eclinm.2020.100296

McMullan C, Retzer A, Slade A, Kyte D, Jones L, Belli A, Calvert M, et al. Care providers’ and patients’ attitudes towards using electronic-patient reported outcomes to support patients with traumatic brain injury: a qualitative study (PRiORiTy). Brain Inj. 2020 Mar 29:1-9. doi: 10.1080/02699052.2020.1740944.

2019

Davies D, Yakoub KM, Scarpa U, Bentley C, Grey M, Hammond D, Sawlani V, Belli A, Di Pietro V. Serum miR-502: A potential biomarker in the diagnosis of concussion in a pilot study of patients with normal structural brain imaging. Journal of Concussion. 2019 Nov;3: doi: 10.1177/2059700219886190

Stapleton CJ, Acharjee A, Irvine HJ, Wolcott ZC, Patel AB, Kimberly WT. High-throughput metabolite profiling: identification of plasma taurine as a potential biomarker of functional outcome after aneurysmal subarachnoid hemorrhage. J Neurosurg. 2019 Nov 22:1-8. doi: 10.3171/2019.9.JNS191346.

Keene D, Alsousou J, Harrison P, Hulley P, Wagland S, Parsons S, et al. Platelet rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo controlled, superiority trial. BMJ 2019 Nov http://dx.doi.org/10.1136/bmj.l6132

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. The Lancet 2019 October 14, 2019 doi: https://doi.org/10.1016/S0140-6736(19)32233-0

Ravi A, Halstead FD, Bamford A, Casey A, Thomson NM, Van Schaik W, Snelson C. Loss of microbial diversity and pathogen domination of the gut microbiota in critically ill patients. BioRxiv Microb Genom. 2019 Sep 1. doi: 10.1099/mgen.0.000293.

Dinsdale, R. J., Hazeldine, J. , Al Tarrah, K. , Hampson, P. , Devi, A., Ermogenous, C. et al. Dysregulation of the actin scavenging system and inhibition of DNase activity following severe thermal injury. Br J Surg. 2019 Sep 10 doi:10.1002/bjs.11310

Chimen M, Evryviadou A, Box CL, Harrison MJ, Hazeldine J, Dib LH, et al. Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation. Haematologica. 2019 Aug 29. pii: haematol.2018.215145. doi: 10.3324/haematol.2018.215145.

Halstead FD, Hadis MA, Marley N, Brock K, Milward MR, Cooper PR, et al. Violet-Blue Light Arrays at 405nm Exert Enhanced Antimicrobial Activity for Photodisinfection of Monomicrobial Nosocomial Related Biofilms. Appl Environ Microbiol. 2019 Aug 23. pii: AEM.01346-19. doi: 10.1128/AEM.01346-19

Stevens AR, Su Z, Toman E, Belli A, Davies D. Optical pupillometry in traumatic brain injury: neurological pupil index and its relationship with intracranial pressure through significant event analysis. Brain Inj. 2019;33(8):1032-1038. doi: 10.1080/02699052.2019.1605621.Bentley C, Hazeldine J, Greig C, Lord J, Foster M. Dehydroepiandrosterone: a potential therapeutic agent in the treatment and rehabilitation of the traumatically injured patient. Burns Trauma. 2019;7:26. doi: 10.1186/s41038-019-0158-z. eCollection 2019.

Orive-Miguel D, Lanka P, Yang L, Tagliabue S, Sudakou A, Samaei S, et al. The BitMap dataset: an open dataset on performance assessment of diffuse optics instruments. Diffuse Optical Spectroscopy and Imaging VII 2019 Jul 11 (Vol. 11074, p. 110741B) doi.org/10.1117/12.2526728

Lanka P, Yang L, Orive-Miguel D, Veesa JD, Tagliabue S, Sudakou A, Samaei S, Forcione M, et al. “The BITMAP exercise: a multi-laboratory performance assessment campaign of diffuse optical instrumentation,” Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 110741A 2019 July 11 ; doi: 10.1117/12.2527120

Yakoub KM, Davies DJ, Su Z, Bentley C, Forcione M, Toman E et al. Investigation into repetitive concussion in sport (RECOS): study protocol of a prospective, exploratory, observational cohort study. BMJ Open. 2019;9:e029883. doi:10.1136/bmjopen-2019-029883

Nicholls SM, Quick JC, Tang S, Loman NJ. Ultra-deep, long-read nanopore sequencing of mock microbial community standards. Gigascience. 2019;8(5). pii: giz043. doi: 10.1093/gigascience/giz043.

Yakoub KM, Lazzarino G, Amorini AM, Caruso G, Scazzone C, Ciaccio M et al. Fructose-1,6-Bisphosphate Protects Hippocampal Rat Slices from NMDA Excitotoxicity. Int J Mol Sci. 2019;20(9). pii: E2239. doi: 10.3390/ijms20092239.

Bravo‑Merodio L, Williams JA, Gkoutos GV and Acharjee A. ‑Omics biomarker identification pipeline for translational medicine. J Transl MeD. 2019;17:155 https://doi.org/10.1186/s12967-019-1912-5

Davies DJ, Clancy M, Dehghani H, Lucas SJE, Forcione M, Yakoub KM et al. Cerebral oxygenation in traumatic brain injury; Can a non-invasive frequency domain near-infrared spectroscopy device detect changes in brain tissue oxygen tension as well as the established invasive monitor? J Neurotrauma. 2019;36(7):1175-1183. doi: 10.1089/neu.2018.5667. Epub 2018 Oct 19

Watson CN, Belli A, and Di Pietro V,. Small Non-coding RNAs: New Class of Biomarkers and Potential Therapeutic Targets in Neurodegenerative Disease. Front Genet. 2019; 10: 364. 2019 Apr 26. doi: 10.3389/fgene.2019.00364

Edlmann E, Thelin EP, Caldwell K, Turner C, Whitfield P, Bulters D et al. Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase. Sci Rep. 2019;9(1):5885. doi: 10.1038/s41598-019-42087-z.

Van Essen TA, Den Boogert HF, Cnossen MC, De Ruiter GC, Haitsma I, Polinder S, Steyerberg EW, et al. Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study. Acta Neurochir (Wien). 2019 Mar;161(3):435-449. doi: 10.1007/s00701-018-3761-z.

Hazeldine J, Dinsdale RJ, Harrison P, Lord JM. Traumatic Injury and Exposure to Mitochondrial-Derived Damage Associated Molecular Patterns Suppresses Neutrophil Extracellular Trap Formation. Front Immunol. 2019;10:685. doi: 10.3389/fimmu.2019.00685. eCollection 2019.

Middlebrook N, Rushton AB, Heneghan NR, Falla D. Measures of central sensitisation and their measurement properties in the adult musculoskeletal trauma population: a protocol for a systematic review and data synthesis. BMJ Open. 2019 Mar 23;9(3):e023204. doi: 10.1136/bmjopen-2018-023204

Qureshi KL, Upthegrove R, Toman E, Sawlani V, Davies DJ, Belli A. Post-traumatic stress disorder in UK civilians with traumatic brain injury: an observational study of TBI clinic attendees to estimate PTSD prevalence and its relationship with radiological markers of brain injury severity. BMJ Open Feb 2019, 9 (2) bmjopen-2018-021675; DOI: 10.1136/bmjopen-2018-021675

Retzer A, Turner GM, Slade A, Kyte D, McMullan C, Jones L, Belli A, Calvert M. Electronic patient reported outcomes to support care of patients with traumatic brain injury: PRiORiTy study qualitative protocol. BMJ Open Jan 2019, 9 (1) bmjopen-2018-024617; DOI: 10.1136/bmjopen-2018-024617

Bown D, Belli A, Qureshi K, Davies D, Toman E, Upthegrove R. Post-traumatic stress disorder and self-reported outcomes after traumatic brain injury in victims of assault. PLoS One. 2019 Feb 7;14(2):e0211684. doi: 10.1371/journal.pone.0211684. eCollection 2019.

Halstead FD, Ahmed Z, Bishop JRB, Oppenheim BA. The potential of visible blue light (405 nm) as a novel decontamination strategy for carbapenemase-producing enterobacteriaceae (CPE). Antimicrob Resist Infect Control. 2019 Jan 17;8:14. doi: 10.1186/s13756-019-0470-1. eCollection 2019.

Turner GM, Slade A, Retzer A, McMullan C, Kyte D, Belli A and Calvert M. An Introduction to Patient Reported Outcome Measures in Trauma. J Trauma Acute Care Surg. 2019;86:314-320. doi: 10.1097/TA.0000000000002102

Blanch RJ, Bishop J, Javidi H, Murray PI. Effect of time to primary repair on final visual outcome after open globe injury. Br J Ophthalmol.2019 Jan 12.pii: bjophthalmol-2017-311559. doi: 10.1136/bjophthalmol-2017-311559. [Epub ahead of print]

Hancox JM, Toman E, Brace-McDonnell SJ, Naumann DN. Patient-centred outcomes for prehospital trauma trials: A systematic review and patient involvement exercise. January 6^th 2019. https://journals.sagepub.com/doi/10.1177/1460408618817912

2018

Hughes EA, Parkes A, Williams RL, Jenkins MJ, Grover LM. Formulation of a covalently bonded hydroxyapatite and poly(ether ether ketone) composite. J Tissue Eng. 2018 Dec 17;9:2041731418815570. doi: 10.1177/2041731418815570. eCollection 2018 Jan-Dec.

Hill LJ, Moakes RJA, Vareechon C, Butt G, Ng A, Brock K, Chouhan G, Vincent RC, Abbondante S, Williams RL, Barnes NM, Pearlman E, Wallace GR, Rauz S, Logan A, Grover LM. Sustained release of decorin to the surface of the eye enables scarless corneal regeneration. NPJ Regen Med. 2018 Dec 21;3:23. doi: 10.1038/s41536-018-0061-4. eCollection 2018.

Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner Net al. Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial. Trials. 2018 Dec 4;19(1):670. doi: 10.1186/s13063-018-3050-4.

Di Pietro V, Yakoub KM, Scarpa U, Di Pietro C, Belli A. MicroRNA Signature of Traumatic Brain Injury: From the Biomarker Discovery to the Point-of-Care. Front Neurol. 2018 Jun 14;9:429. doi: 10.3389/fneur.2018.00429. eCollection 2018.

Davies DJ, Clancy M, Dehghani H, Lucas SJE, Forcione M, Yakoub KM, Belli A. Cerebral oxygenation in traumatic brain injury; Can a non-invasive frequency domain near-infrared spectroscopy device detect changes in brain tissue oxygen tension as well as the established invasive monitor? J Neurotrauma.2018 Oct 19.doi: 10.1089/neu.2018.5667. [Epub ahead of print]

Yakoub KM, O’Halloran P, Davies DJ, Bentley C, Watson CN, Forcione M et al. Study of Concussion in Rugby Union through MicroRNAs (SCRUM): a study protocol of a prospective, observational cohort study. BMJ Open 2018;8:e024245. doi:10.1136/bmjopen-2018-024245

Sullivan J, Mirbahai L, Lord JM. Major trauma and acceleration of the ageing process. Ageing Res Rev. 2018 Dec;48:32-39. doi: 10.1016/j.arr.2018.10.001. Epub 2018 Oct 11.

Di Pietro V, Porto E, Ragusa M, Barbagallo C, Davies D, Forcione M et al. Salivary MicroRNAs: Diagnostic Markers of Mild Traumatic Brain Injury in Contact-Sport. Front MolNeurosci. 2018 Aug 20;11:290. doi: 10.3389/fnmol.2018.00290. eCollection 2018.

Begum G, O’Neill J, Chaudhary R, Blachford K, Snead DRJ, Berry M et al. Altered Decorin Biology in Proliferative Vitreoretinopathy: A Mechanistic and Cohort Study. Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):4929-4936. doi: 10.1167/iovs.18-24299

Kuravi SJ, Harrison P, Rainger GE, Nash GB.Ability of Platelet-Derived Extracellular Vesicles to Promote Neutrophil-Endothelial Cell Interactions. Inflammation.2018 Sep 14.doi: 10.1007/s10753-018-0893-5. [Epub ahead of print]

McCarthy EM, Floyd H, Addison O, Zhang ZJ , Oppenheimer PG, Grover LM. Influence of Cobalt Ions on Collagen Gel Formation and Their Interaction with Osteoblasts. ACS Omega.2018;3(8):10129–10138. DOI: 10.1021/acsomega.8b01048. Publication Date (Web): August 30, 2018

Duggal NA, Snelson C, Shaheen U, Pearce V, Lord JM. Innate and adaptive immune dysregulation in critically ill ICU patients. Sci Rep. 2018 Jul 5;8(1):10186. doi: 10.1038/s41598-018-28409-7.

Hutchings SD, Naumann DN, Hopkins P, Mellis C, Riozzi P, Sartini S et al. Microcirculatory Impairment Is Associated With Multiple Organ Dysfunction Following Traumatic Hemorrhagic Shock: The MICROSHOCK Study. Crit Care Med. 2018 Jun 27. doi: 10.1097/CCM.0000000000003275. [Epub ahead of print]

Naumann DN, Hazeldine J, Bishop J, Midwinter MJ, Harrison P, Nash G et al. Impact of plasma viscosity on microcirculatory flow after traumatic haemorrhagic shock: A prospective observational study. ClinHemorheolMicrocirc. 2018 May 19. doi: 10.3233/CH-180397. [Epub ahead of print]

Forcione M, Colonnese C and Belli A. Cerebral Hemodynamic Influences in Task-Related Functional Magnetic Resonance Imaging and Near-Infrared Spectroscopy in Acute Sport-Related Concussion: A Review. J. Imaging 2018, 4, 59; doi:10.3390/jimaging4040059

Boulton AJ, Lewis CT, Naumann DN, Midwinter MJ. Prehospital haemostatic dressings for trauma: a systematic review. Emerg Med J. 2018 May 4. pii: emermed-2018-207523. doi: 10.1136/emermed-2018-207523. [Epub ahead of print]

Al-Tarrah K, Hewison M, Moiemen N, Lord JM. Vitamin D status and its influence on outcomes following major burn injury and critical illness. Burns Trauma. 2018 Apr 16;6:11. doi: 10.1186/s41038-018-0113-4. eCollection 2018.

Rushton AB, Evans DW, Middlebrook N, Heneghan NR, Small C, Lord J, Patel JM, Falla D. Development of a screening tool to predict the risk of chronic pain and disability following musculoskeletal trauma: protocol for a prospective observational study in the United Kingdom. BMJ Open. 2018 Apr 28;8(4):e017876. doi: 10.1136/bmjopen-2017-017876

Howroyd F. Supporting the patient innovator. ICU Management & Practice, Volume 18 – Issue 1, Spring 2018

Naumann DN, Hazeldine J, Davies DJ, Bishop J, Midwinter MJ, Belli A et al. Endotheliopathy of trauma is an on-scene phenomenon, and is associated with multiple organ dysfunction syndrome: a prospective observational study. Shock. 2018 Apr;49(4):420-428. doi: 10.1097/SHK.0000000000000999

McWilliams D, Jones C, Atkins G, Hodson J, Whitehouse T, Veenith T, Reeves E, Cooper L, Snelson C. Earlier and enhanced rehabilitation of mechanically ventilated patients in critical care: A feasibility randomised controlled trial. J Crit Care. 2018 Apr;44:407-412. doi: 10.1016/j.jcrc.2018.01.001. Epub 2018 Jan 4

Cato LD, Wearn CM, Bishop JRB, Stone MJ, Harrison P, Moiemen N. Platelet count: a predictor of sepsis and mortality in severe burns? Burns. 2018 Mar;44(2):288-297. doi: 10.1016/j.burns.2017.08.015. Epub 2017 Oct 9

Montague SJ, Delierneux C, Lecut C, Layios N, Dinsdale RJ, Lee CS et al. Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI. Blood Adv. 2018 Feb 13;2(3):240-251. doi: 10.1182/bloodadvances.2017011171.

Calvert M, Kyte D, Mercieca-Bebber R, Slade A, Chan A-W, King M ; and the SPIRIT-PRO Group. Guidelines for Inclusion of Patient-Reported Outcomes in Clinical Trial Protocols: The SPIRIT-PRO Extension. JAMA. 2018 Feb 6;319(5):483-494. doi: 10.1001/jama.2017.21903.

Jain M, Koren S, Miga KH, Quick J, Rand AC, Sasani TA et al. Nanopore sequencing and assembly of a human genome with ultra-long reads. Nat Biotechnol. 2018;36(4):338-345. doi: 10.1038/nbt.4060. Epub 2018 Jan 29

Naumann DN, Hazeldine J, Midwinter MJ, Hutchings SD, Harrison P. Poor microcirculatory flow dynamics are associated with endothelial cell damage and glycocalyx shedding following traumatic hemorrhagic shock. J Trauma Acute Care Surg. 2018;84(1):81-88

Naumann DN, Hancox JM, Raitt J, Smith IM, Crombie N, Doughty H et al. What fluids are given during air ambulance treatment of patients with trauma in the UK, and what might this mean for the future? Results from the RESCUER observational cohort study. BMJ Open Jan 2018, 8 (1) e019627; DOI: 10.1136/bmjopen-2017-019627

2017

Smith IM, Crombie N, Bishop JR, McLaughlin A, Naumann DN, Herbert M et al. RePHILL: protocol for a randomised controlled trial of pre-hospital blood product resuscitation for trauma. Transfus Med. 2017 Nov 28. doi: 10.1111/tme.12486. [Epub ahead of print]

Naumann DN, Hazeldine J, Dinsdale RJ, Bishop JR, Midwinter MJ, Harrison P, et al. Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study. PLoS One. 2017 Dec 19;12(12):e0189870. doi: 10.1371/journal.pone.0189870. eCollection 2017

Cnossen MC, Huijben JA, van der Jagt M, Volovici V, van Essen T, Polinder S et al. Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotraumacenters participating in the CENTER-TBI study. Crit Care. 2017;21(1):233. doi: 10.1186/s13054-017-1816-9.

Roper LS, Nightingale P, Su Z, Mitchell JL, Belli A, Sinclair AJ. Disability from posttraumatic headache is compounded by coexisting posttraumatic stress disorder. J Pain Res. 2017 Aug 21;10:1991-1996. doi: 10.2147/JPR.S129808. eCollection 2017.

Di Pietro V, Lazzarino G, Amorini AM, Signoretti S, Hill LJ, Porto E et al. Fusion or Fission: The Destiny of Mitochondria In Traumatic Brain Injury of Different Severities. Sci Rep. 2017 Aug 23;7(1):9189. doi: 10.1038/s41598-017-09587-2.

Maas AIR, Menon DK, Adelson PD, Andelic N, Bell MJ, Belli A et al.Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. Lancet Neurol. 2017;16(12):987-1048. doi: 10.1016/S1474-4422(17)30371-X. Epub 2017 Nov 6

Lazzarino G, Longo S, Amorini AM, Di Pietro V, D’Urso S, Lazzarino G et al. Single-step preparation of selected biological fluids for the high performance liquid chromatographic analysis of fat-soluble vitamins and antioxidants. J Chromatogr A.2017;1527:43-52. doi: 10.1016/j.chroma.2017.10.053.

Kuravi SJ, Yates CM, Foster M, Harrison P, Hazeldine J, Hampson P et al. Changes in the pattern of plasma extracellular vesicles after severe trauma. PLoS One. 2017;12(8):e0183640. doi: 10.1371/journal.pone.0183640. eCollection 2017

de Cogan F, Hill LJ, Lynch A, Morgan-Warren PJ et al. Topical Delivery of Anti-VEGF Drugs to the Ocular Posterior Segment Using Cell-Penetrating Peptides. Invest Ophthalmol Vis Sci. 2017;58(5):2578-2590. doi: 10.1167/iovs.16-20072

Di Pietro V, Ragusa M, Davies D, Su Z, Hazeldine J, Lazzarino G, et al. MicroRNAs as Novel Biomarkers for the Diagnosis and Prognosis of Mild and Severe Traumatic Brain Injury. J Neurotrauma. 2017 Jun 1;34(11):1948-1956.doi: 10.1089/neu.2016.4857. Epub 2017 Apr 10.

Dinsdale R, Devi A, Hampson P, Wearn C, Bamford A, Hazeldine J, Bishop J, Ahmed S, Watson C, Lord JM, Moiemen N, Harrison P (2017) Changes in novel haematological parameters following thermal injury A prospective observational cohort study. Sci Rep. 2017 Jun 12;7(1):3211. doi: 10.1038/s41598-017-03222-w

Eisenstein N, Naumann DN, Burns DS, Stapley SA, Draper H. Left of Bang Interventions in Trauma: Ethical Implications for Military Medical Prophylaxis. J Med Ethics.2017 Aug 16.pii: medethics-2017-104299. doi: 10.1136/medethics-2017-104299. [Epub ahead of print]

Hazeldine J, Naumann DN, Toman E, Davies D, Bishop JRB, Su Z, et al. Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study. PLoS Med 14(7): e1002338. https://doi.org/10.1371/journal.pmed.1002338

Faria NR, Quick J, Claro IM, Thézé J, de Jesus JG, Giovanetti M, et al. Establishment and cryptic transmission of Zika virus in Brazil and the Americas. Nature. 2017 Jun 15;546(7658):406-410. doi: 10.1038/nature22401.

Grubaugh ND, Ladner JT, Kraemer MUG, Dudas G, Tan AL, Gangavarapu K, et al. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. Nature. 2017 Jun 15;546(7658):401-405. doi: 10.1038/nature22400.

Ter Horst B, Chouhan G, Moiemen NS, Grover LM. Advances in keratinocyte delivery in burn wound care. Adv Drug Deliv Rev. 2017 Jun 28. pii: S0169-409X(17)30096-0. doi: 10.1016/j.addr.2017.06.012. [Epub ahead of print]

Tan CL, Alavi SA, Baldeweg SE, Belli A, Carson A, Feeney C et al. The screening and management of pituitary dysfunction following traumatic brain injury in adults: British Neurotrauma Group guidance. J NeurolNeurosurg Psychiatry. 2017;88(11):971-981. doi: 10.1136/jnnp-2016-315500. Epub 2017 Aug 31.

James M. Hancox, Julian Spiers, Nicholas Crombie, and David N. Naumann. Unilateral Dilated Pupil and Spontaneous Cardiac Arrest with Successful Bystander Resuscitation.
Case Rep Emerg Med. 2017;2017:4071531. doi: 10.1155/2017/4071531.

Trzaska WJ, Wrigley HE, Thwaite JE, May RC. Species-specific antifungal activity of blue light. Sci Rep. 2017 Jul 4;7(1):4605. doi: 10.1038/s41598-017-05000-0.

Halstead FD, Webber MA, Oppenheim BA. Use of an engineered honey to eradicate pre-formed biofilms of important wound pathogens: an in vitro study. J Wound Care. 2017;26(8):442-450. doi: 10.12968/jowc.2017.26.8.442

Halstead FD, Kwang Chear Lee, Kwei J, Dretzke J, Oppenheim BA, Moiemen NS. A systematic review of quantitative burn wound microbiology in the management of burns patients. Burns.
Burns.2017 Aug 4.pii: S0305-4179(17)30360-1. doi: 10.1016/j.burns.2017.06.008. [Epub ahead of print]

Hill LJ, Di Pietro V, Hazeldine J, Davies D, Tomman E, Logan A, Belli A. Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury. Sci Rep. 2017 Jul 10;7(1):5002. doi: 10.1038/s41598-017-04722-5.

Naumann DN, Vincent LE, Pearson N, Beaven A, Smith IM, Smith K, Toman E, Dorrance HR, Porter K, Wade CE, Cotton BA, Holcomb JB, Midwinter MJ. An adapted Clavien-Dindo scoring system in trauma as a clinically meaningful non-mortality endpoint. J Trauma Acute Care Surg. 2017;83(2):241-248. doi: 10.1097/TA.0000000000001517.

Hampson P, Dinsdale RJ, Wearn CM, Bamford A, Bishop J, Hazeldine J, et al. Neutrophil dysfunction, immature granulocytes and NETosis are early biomarkers of sepsis in burn injured patients. Ann Surg. 2017;265(6):1241-1249. doi: 10.1097/SLA.0000000000001807

Dryden MS, Cooke J, Salib RJ, Holding RE, Biggs T, Salamat AA, et al. Reactive oxygen: a novel antimicrobial mechanism for targeting biofilm-associated infection. J Glob Antimicrob Resist.2017;8:186-191

Townsend L, Williams RL, Anuforom O, Berwick MR, Halstead F, Hughes E, et al. Antimicrobial peptide coatings for hydroxyapatite: electrostatic and covalent attachment of antimicrobial peptides to surfaces.J R Soc Interface. 2017 Jan;14(126). DOI: 10.1098/rsif.2016.0657

Toman E, Bishop JR, Davies DJ, Su Z, Criseno S, Mason A, et al. Vitamin D Deficiency in Traumatic Brain Injury and Its Relationship with Severity of Injury and Quality of Life: A Prospective, Observational Study. J Neurotrauma. 2017;34(7):1448-1456. doi: 10.1089/neu.2016.4494.

Davies DJ, Clancy M, Lighter D, Balanos GM, Lucas SJ, Dehghani H et al. Frequency-domain vs continuous-wave near-infrared spectroscopy devices: a comparison of clinically viable monitors in controlled hypoxia. J ClinMonitComput.

2016

Hutchings SD, Naumann DN, Watts S, Wilson C, Burton C, Wendon J, et al. Microcirculatory perfusion shows wide inter-individual variation and is important in determining shock reversal during resuscitation in a porcine experimental model of complex traumatic hemorrhagic shock. Intensive Care Med Exp. 2016;4(1):17.

Naumann DN, Bowley DM, Midwinter MJ, Walker A, Pallister I. High-Fidelity Simulation Model of Pelvic HemorrhagicTrauma:The Future for Military Surgical Skills Training? Mil Med. 2016;181, 11/12:1407.

Naumann DN, Mellis C, Husheer SL, Hopkins P, Bishop J, Midwinter MJ, et al. Real-time point of care microcirculatory assessment of shock: design, rationale and application of the point of care microcirculation (POEM) tool. Crit Care. 2016;20(1):310.

Naumann DN, Beaven A, Dretzke J, Hutchings S, Midwinter MJ. Searching for the optimal fluid to restore microcirculatory flow dynamics after haemorrhagic shock: a systematic review of preclinical studies. Shock. 2016;46(6):609-622.

Naumann DN, Smith IM, Beaven A, Midwinter MJ. The term ‘prehospital’ must be justified when reporting animal studies of traumatic hemorrhagic shock. J Trauma Acute Care Surg. 2016; 81(2):394-396.

Eisenstein N, Naumann DN, Bowley DM, Midwinter MJ. Pretrauma Interventions in Force Health Protection: Introducing the “Left of Bang” Paradigm. J Spec Oper Med.2016;16(4)59–63

Naumann DN, Mellis C, Smith IM, Mamuza J, Skene I, Harris T, et al. Safety and feasibility of sublingual microcirculation assessment in the emergency department for civilian and military patients with traumatic haemorrhagic shock: a prospective cohort study. BMJ Open. 2016;6(12): e014162

James M Hancox, Mark J Midwinter, David N Naumann. Show me the evidence! Engaging with science in the pre-hospital environment.
Journal of Paramedic Practice, Vol. 8, Iss. 7, 01 Jul 2016, pp 330 – 331

Davies DJ, Clancy M, Lighter D, Balanos GM, Lucas SJ, Dehghani H, Su Z, Forcione M, Belli A. Frequency-domain vs continuous-wave near-infrared spectroscopy devices: a comparison of clinically viable monitors in controlled hypoxia. J ClinMonitComput.2016 Oct 24. DOI: 10.1007/s10877-016-9942-5
[Epub ahead of print]

Toman E, Bishop JR, Davies DJ, Su Z, Criseno S, Mason A, et al. Vitamin D Deficiency in Traumatic Brain Injury and Its Relationship with Severity of Injury and Quality of Life: A Prospective, Observational Study.J Neurotrauma.2016 Dec 20.doi: 10.1089/neu.2016.4494

Hazeldine J, Hampson P, Lord JM. The diagnostic and prognostic value of systems biology research in major traumatic and thermal injury: a review. Burns Trauma. 2016;4:33.
DOI 10.1186/s41038-016-0059-3

Clancy M, Belli A, Davies D, Lucas SJ, Su Z, Dehghani H. Improving the quantitative accuracy of cerebral oxygen saturation in monitoring the injured brain using atlas based Near Infrared Spectroscopy models. J Biophotonics.2016;9(8):812-26.

Davies DJ, Clancy M, Lighter D, Balanos GM, Lucas SJ, Dehghani H, Su Z, Forcione M, Belli A. Frequency-domain vs continuous-wave near-infrared spectroscopy devices: a comparison of clinically viable monitors in controlled hypoxia. J ClinMonitComput.2016 Oct 24. DOI: 10.1007/s10877-016-9942-5
[Epub ahead of print]

Toman E, Bishop JR, Davies DJ, Su Z, Criseno S, Mason A, et al. Vitamin D Deficiency in Traumatic Brain Injury and Its Relationship with Severity of Injury and Quality of Life: A Prospective, Observational Study.J Neurotrauma.2016 Dec 20.doi: 10.1089/neu.2016.4494

Lewis CT, Naumann DN, Crombie N, Midwinter MJ. Prehospital point-of-care lactate following trauma: A systematic review. J Trauma Acute Care Sur.2016; 81 (4)748–755.

Eisenstein N, Naumann DN, Bowley DM, Midwinter MJ. Pretrauma Interventions in Force Health Protection: Introducing the “Left of Bang” Paradigm. J Spec Oper Med.2016;16(4)59–63

Michael Clancy, Antonio Belli, David Davies, Samuel J. E. Lucas, Zhangjie Su, Hamid Dehghani. Improving the quantitative accuracy of cerebral oxygen saturation in monitoring the injured brain using atlas based Near Infrared Spectroscopy models. Journal of Biophotonics. 22 Mar 2016. DOI: 10.1002/jbio.201500302

Hutchings S, Naumann DN, Harris T, Wendon J, Midwinter MJ. Observational study of the effects of traumatic injury, haemorrhagic shock and resuscitation on the microcirculation: a protocol for the MICROSHOCK study. BMJ Open 2016 6:e010893 doi:10.1136/bmjopen-2015-010893

Halstead FD, Webber MA, Rauf M, Burt R, Dryden M, Oppenheim BA. In vitro activity of an engineered honey, medical-grade honeys, and antimicrobial wound dressings against biofilm-producing clinical bacterial isolates. J Wound Care. 2016 Feb; 25(2):93-102. doi: 10.12968/jowc.2016.25.2.93.

Real-time, portable genome sequencing for Ebola surveillance, Nature. 2016 Feb 11;530(7589):228-32. doi: 10.1038/nature16996. Epub 2016 Feb 3.Quick J, Loman NJ, Duraffour S, Simpson JT, Severi E, Cowley L, Bore JA, Koundouno R, Dudas G, Mikhail A, Ouédraogo N, Afrough B, Bah A, Baum JH,Becker-Ziaja B, Boettcher JP, Cabeza-Cabrerizo M, Camino-Sánchez Á, Carter LL, Doerrbecker J, Enkirch T, García-Dorival I, Hetzelt N, Hinzmann J, Holm T,Kafetzopoulou LE, Koropogui M, Kosgey A, Kuisma E, Logue CH, Mazzarelli A, Meisel S, Mertens M, Michel J, Ngabo D, Nitzsche K, Pallasch E, PatronoLV,Portmann J, Repits JG, Rickett NY, Sachse A, Singethan K, Vitoriano I, Yemanaberhan RL, Zekeng EG, Racine T, Bello A, Sall AA, Faye O, Faye O,Magassouba N, Williams CV, Amburgey V, Winona L, Davis E, Gerlach J, Washington F, Monteil V, Jourdain M, Bererd M, Camara A, Somlare H, Camara A,Gerard M, Bado G, Baillet B, Delaune D, Nebie KY, Diarra A, Savane Y, Pallawo RB, Gutierrez GJ, Milhano N, Roger I, Williams CJ, Yattara F, Lewandowski K,Taylor J, Rachwal P, Turner DJ, Pollakis G, Hiscox JA, Matthews DA, O’Shea MK, Johnston AM, Wilson D, Hutley E, Smit E, Di Caro A, Wölfel R, StoeckerK,Fleischmann E, Gabriel M, Weller SA, Koivogui L, Diallo B, Keïta S, Rambaut A, Formenty P, Günther S, Carroll MW. Real-time, portable genome sequencing for Ebola surveillance.

2015

Naumann DN, Clarkson A, Midwinter MJ, Crombie N. Prehospital rapid sequence induction following trauma in the era of regional networks for major trauma. Eur J Emerg Med. 2015. doi: 10.1097/MEJ.0000000000000364.

Smith IM, Naumann DN, Guyver P, Bishop J, Davies S, Lundy JB and Bowley DM. Inter-observer variability in injury severity scoring after combat trauma: different perspectives, different values? Journal of Special Operations Medicine. 2015;15(2):86-93.

Naumann DN, Dretizke J, Hutchings S, Midwinter MJ. Protocol for a systematic review of the impact of resuscitation fluids on the microcirculation after haemorrhagic shock in animal models. 2015 Aug. Available online at http://www.dcn.ed.ac.uk/camarades/research.html#protocols

Smith IM, Naumann DN, Marsden MER, Ballard M and Bowley DM. Scanning and War: Utility of FAST and CT in the assessment of battlefield abdominal trauma. Annals of Surgery. 2015 Aug;262(2):389-96. Epub ahead of print.

Toman E, Harrisson S, Belli T. Biomarkers in traumatic brain injury: a review. J R Army Med Corps.2015 Nov 2.pii: jramc-2015-000517. doi: 10.1136/jramc-2015-000517.

Toman E, Beaven A, Balogun M, Porter K. Ovarian vein thrombosis in a polytrauma patient. BMJ Case Rep. 2015 Dec 18;2015. pii: bcr2015213071. doi: 10.1136/bcr-2015-213071.

Jansen JO, Morrison JJ, Tai NRM, Midwinter MJ. A survey of major trauma centre staffing in England. J R Army Med Corps 2015;161:341–344. doi:10.1136/jramc-2014-000350.

Hazeldine J, Lord JM, Belli A. Traumatic brain injury and peripheral immune suppression: primer and prospectus. Front. Neurol. 2015 Nov 05. 6:235. doi: 10.3389/fneur.2015.00235.

Hazeldine J, Lord JM, Hampson P. Immunesenescence and inflammaging: A contributory factor in the poor outcome of the geriatric trauma patient. Ageing Res Rev. 2015 Oct 17. pii: S1568-1637(15)30028-3. doi: 10.1016/j.arr.2015.10.003. Epub ahead of print.

Niebel M, Quick J, Prieto AM, Hill RL, Pike R, Huber D, David M, Hornsey M, Wareham D, Oppenheim B, Woodford N, van Shaik W, Loman N. Deletions in a ribosomal protein-coding gene are associated with tigecycline resistance in Enterococcus faecium. 2015 Aug. Epub ahead of print.

Halstead FD, Rauf M, Moiemen NS, Bamford A, Wearn CM, Fraise AP, Lund PA, Oppenheim BA, Webber MA. The antibacterial activity of acetic acid against biofilm-producing pathogens of relevance to burns patients. PLoS One.2015 Sep. Epub.

Kelly M, Williams R, Aojula A, O’Neill J, Trzincska Z, Grover LM, Scott RA, Peacock AF, Logan A, Stamboulis A, de Cogan F. Peptide Aptamers: Novel Coatings for Orthopaedic Implants. Materials Science and Engineering C. 2015 Sep;54:84-93.

Hammond D, Davies DJ, Su Z. Do we forget to treat concussion? Faculty Dental Journal. 2015. http://dx.doi.org/10.1308/204268515X14174408396046

Halstead FD, Rauf M, Moiemen NS, Bamford A, Wearn CM, Fraise AP, Oppenheim BA, Webber MA. Antimicrobial dressings: Comparison of the ability of a panel of dressings to prevent biofilm formation by key burn wound pathogens.Burns. 2015 Jul. Epub ahead of print.

Hazeldine J, Hampson P, AdeusiOpoku F, Foster M and Lord JM. N-formyl peptides drive mitochondrial damage associated molecular pattern induced neutrophil activation through ERK1/2 and P38 MAP Kinase signalling pathways.Injury. 2015 Jun;46(6):975-84.

Erika Check Hayden. Pint-sized DNA sequencer impresses first users. Nature. 2015 May;521:15–16.

Penn-Barwell JG, Roberts SAG, Bishop JRB, Midwinter MJ. Improved survival in UK combat casualties from Iraq and Afghanistan: 2003-2012. J Trauma Acute Care Surg. 2015:78(5);1-7.

Alshehri OM, Montague S, Watson S, Carter P, Sarker N, Manne BK, Miller JL, Herr AB, Pollitt AY, O’Callaghan CA, Kunapuli SP, Arman M, Hughes CE, Watson SP. Activation of Glycoprotein VI (GPVI) and C-type Lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands. Biochem J. 2015 Apr; Epub ahead of print.

Smith IM, Beech ZK, Lundy JB and Bowley DM. A prospective observational study of abdominal injury management in contemporary military operations: Damage control laparotomy is associated with high survivability and low rates of fecal diversion. Annals of Surgery. 2015 Apr;261(4):765-73. Epub ahead of print.

Davies D et al. Near Infrared Cerebral Spectroscopy in the monitoring of adult patients with traumatic brain injury: A review of the current literature. J. Neurotrauma. 2015 Apr; Epub ahead of print.

Chaudhary R, Upendran M, Campion N, Yeung A, Blanch R, Morgan-Warren P, Gibb I, Nelson T and Scott R. The role of computerised tomography in predicting visual outcome in ocular trauma patients. Eye. 2015 Apr; Epub ahead of print.

Penn-Barwell JG, Peleki A, Chen YF, Bishop JRB, Midwinter MJ, Rickard RF. Intraoperative fluid irrigation for traumatic wounds (Protocol). Cochrane Review (protocol). Available online at http://www.cochrane.org/CD011555/WOUNDS_intraoperative-fluid-irrigation-for-traumatic-wounds

2014

Hazeldine J, Hampson P, Lord JM. The impact of trauma on neutrophil function. Injury, 2014.

Su Z, Davies DJ, et al. Self-reported outcomes after head injury – assault as a red flag for adverse outcomes. European Journal of Trauma and Emergency Surgery. 2014, 40 (Suppl 1):S12

Davies DJ, Su Z, et al. Traumatic brain injury – can the initial Marshall grading of CT scan be useful in predicting self-reported outcomes after survival? British Journal of Neurosurgery. 2014, 28(2): 168.

Westwood J, Burnett M, Spratt D, et al. The hospital microbiome project: meeting report for the UK science and innovation network UKUSA workshop ‘beating the superbugs: hospital microbiome studies for tackling antimicrobial resistance’. Standards in Genomic Sciences 2014. 2013 Oct;9:12

Salter S, Cox MJ, Turek EM, Calus ST, Cookson WO, Moffatt MF, Turner P, Parkhill J, Loman N, Walker AW. Reagent contamination can critically impact sequence-based microbiome analyses. BMC Biol. 2014 Nov;12:87

Halachev MR, Chan JZ, Constantinidou CI, Cumley N, Bradley C, Smith-Banks M, Oppenheim B, Pallen MJ. (2014). Genomic Epidemiology of a Protracted Hospital Outbreak caused by Multi-Drug-Resistant Acinetobacter baumannii in Birmingham, England. Genome Med. 2014 Nov;6(11):70

Quick J, Cumley N, Wearn CM, Niebel M, Constantinidou C, Thomas CM, Pallen MJ, Moiemen NS, Bamford A, Oppenheim B, Loman NJ. Seeking the source of Pseudomonas aeruginosa infections in a recently opened hospital: a role for whole-genome sequencing. BMJ Open. 2014 Nov;4(11)

Alneberg J, Bjarnason BS, de Bruijn I, Schirmer M, Quick J, Ijaz UZ, Lahti L, Loman NJ, Andersson AF & Quince C . Binning metagenomiccontigs by coverage and composition. Nature Methods. 2014, 11: 1144–1146

Mendoza L, Vilela R, Voelz K, Ibrahim AS, Voigt K, Lee SC. Human fungal pathogens of mucorales and entomophthorales. Cold Spring HarbPerspect Med. 2014

Voelz K, Johnston SA, Smith LM, Hall RA, May RC. “Division of Labour” in response to host oxidative burst drives a fatalCryptococcusgattii outbreak. Nat Commun. 2014 Oct 17;5:5194

Quick J, Quinlan AR, Loman NJ. A reference bacterial genome dataset generated on the MiniION portable single molecule nanopore sequencer. Gigascience. 2014 Oct 20;3:22

Dretzke J, Smith IM, James R, Midwinter MJ. Protocol for a systematic review of the clinical effectiveness of pre-hospital blood components compared to other resuscitative fluids in patients with major traumatic haemorrhage. Syst Rev. 2014 Oct 24, 3(1):123

Lord JM, Midwinter MJ, Chen YF, Belli A, Brohi K, Kovacs EJ, Koenderman L, Kubes P, Lilford RJ. The systemic immune response to trauma: an overview of pathophysiology and treatment. Lancet. 2014. 384:1455-1465

El Ghoul W, HarrissonS, Belli A. (2014). Autologous cranioplasty following decompressive craniectomy in the trauma setting. British journal of neurosurgery. 2014 Oct;0:1-6

Aisling Clarkson. Trauma Research – Delivering in an Emergency Setting. Faculty World eMagazine. Sept 2014 issue

O’Reilly DJ, Morrison JJ, Jansen JO, Nordmann G, Rasmussen TE, Midwinter MJ, Doughty H. Initial UK experience of prehospital blood transfusion in combat casualties. J Trauma Acute Care Surg. 2014, 77: S66 – S70

O’Reilly DJ, Morrison JJ, Jansen JO, Apodaca AN, Rasmussen TE, Midwinter MJ. Prehospital blood transfusion in the en route management of severe combat trauma: A matched cohort study. J Trauma Acute Care Surg. 2014;77:S114–S120

Sabiiti W, Robertson E, Beale MA, Johnston SA, Brouwer AE, Loyse A, Jarvis JN, Gilbert AS, Fisher MC, Harrison TS, May RC, Bicanic T. Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis. J. Clin Investigation 2014;124(5):2000

Quick J, Constantinidou C, Pallen MJ, Oppenheim B, Loman NJ. Draft Genome Sequence of Elizabethkingiameningoseptica Isolated from a Traumatic Wound. Genome Announc. 2014 May 8;2(3)

Bulstrode H, Nicoll JA, Hudson G, Chinnery PF, Di Pietro V, Belli A. Mitochondrial DNA and traumatic brain injury. Annals of neurology. 2014; 75(2): 186-195

Morrison JJ, Stannard A, Midwinter MJ, Sharon DJ, Eliason JL, Rasmussen TE.Prospective evaluation of the correlation between torso height and aortic anatomy in respect of a fluoroscopy free aortic balloon occlusion system. Surgery. 2014 Jun;155(6):1044-51. doi: 10.1016/j.surg.2013.12.036. Epub 2014 Jan.

Fries CA, Ayalew Y, Penn-Barwell JG, Porter K, Jeffery SL, Midwinter MJ. Prospective randomised controlled trial of nanocrystalline silver dressing versus plain gauze as the initial post-debridement management of military wounds on wound microbiology and healing. Injury. 2014 Jul;45(7):1111-6. doi: 10.1016/j.injury.2013.12.005. Epub 2013 Dec.

Kolias AG, Bulters DO, Cowie CJ, et al. British Neurosurgical Trainee Research Collaborative; British Neurotrauma Group; UKCRR Collaborative Group. Proposal for establishment of the UK Cranial Reconstruction Registry (UKCRR). Br J Neurosurg. 2014 Jun;28(3):310-4. doi: 10.3109/02688697.2013.859657

2013

Voelz K, Ma H, Phadke S, Byrnes EJ, Zhu P, et al. Transmission of Hypervirulence traits via sexual reproduction within and between lineages of the human fungal pathogen cryptococcusgattii. PLoS Genet. 2013;9(9):e1003771. doi: 10.1371/journal.pgen.1003771. Epub 2013 Sep 5

Blanch RJ, Good PA, Shah P, Bishop JR, Logan A, Scott RA. Visual outcomes after blunt ocular trauma.Ophthamol. 2013;120:1588 -91

Mendelow AD, Gregson BA, Rowan EN, Murray GD, Gholkar A, Mitchell PM; STICH II Investigators. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): a randomised trial. Lancet. 2013 Aug 3;382(9890):397-408. doi: 10.1016/S0140-6736(13)60986-1. Erratum in: Lancet. 2013 Aug 3;382(9890):396

Fraise AP, Wilkinson MA, Bradley CR, Oppenheim B, Moiemen N.The antibacterial activity and stability of acetic acid. J. Hosp. Infect. 2013;84(4):329–31

Scott R. The Eye in War. Internat Rev Armed Forces Med Services. 2013;86:17-24

Vagnozzi R, Signoretti S, Floris R, et al. Decrease in N-acetylaspartate following concussion may be coupled to decrease in creatine. J Head Trauma Rehabil. 2013 July-Aug;28(4):284-92

Kolias AG, Scotton WJ, Belli A, et al. UK Neurosurgical Research Network; RESCUE-ASDH collaborative group. Surgical management of acute subdural haematomas: current practice patterns in the United Kingdom and the Republic of Ireland. Br J Neurosurg. 2013 Jun;27(3):330-3

Jansen JO, Lord JM, Thickett DR, Midwinter MJ, McAuley DF, Gao F. Clinical review: Statins and trauma–a systematic review. Crit Care. 2013 May 29;17(3):227. doi: 10.1186/cc12499

Zaben M, El Ghoul W, Belli A. Post-traumatic head injury pituitary dysfunction. DisabilRehabil. 2013 Mar;35(6):522-5

Penn-Barwell JG, Bennett PM, Fries CA, Kendrew JM, Midwinter MJ, Rickard RF. Severe open tibia fractures in combat trauma: management and preliminary outcomes. Bone Joint J. 2013 Jan;95-B(1):101-5

2012

Chan JZ, Halachev MR, Loman NJ, Constantinidou C, Pallen MJ. Defining bacterial species in the genomic era: insights from the genus Acinetobacter. BMC Microbiol. 2012 Dec;12:302

Chan JZ, Pallen MJ, Oppenheim B, Constantinidou C. Genome sequencing in clinical microbiology. Nat Biotechnol. 2012 Nov;30(11):1068-71

Morrison JJ, Ross JD,Dubose JJ, Jansen JO, Midwinter MJ & Rasmussen TE. Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury. Arch Surg. 2012;E2-E8