Research Forum

10 November 2015

Research Forum
Date: Tuesday 10 November 2015
Time: 09:30–11:00
Venue: IBR Seminar Room (N143), Medical School, University of Birmingham

The next NIHR Surgical Reconstruciton and Microbiology Research Centre Research Forum will be held on Tuesday, November 10, in IBR seminar room (N143) at the Medical School.

Speakers this week are:

Dr Janine Dretzke (Systematic Reviewer, NIHR SRMRC, UoB): A brief introduction to some key methodological aspects of systematic reviews and their role in research.

Robert Dinsdale (PhD student, Healing Foundation Birmingham Burns Research Centre, UoB): NETosis during post-thermal injury sepsis – Major thermal injury results in immune dysfunction increasing the risk of sepsis. Central to host defence and innate immunity are neutrophils. Neutrophil extracellular traps (NETs) are an emerging area of innate immunity. NETosis results in the extrusion of nuclear material, decorated in granular proteins and modified histones e.g. citrullinated histone H3 (Cit H3), to the exterior of the cell. NETs primarily function to ensnare bacteria but uncontrolled NETosis is detrimental and can promote thrombosis.

Dr Jon Bishop (Research Fellow in Statistics – NIHR SRMRC, UoB): Statistical reasons why most medical research might be wrong – This talk will examine some of the arguments made by John Ioannidis in a seminal paper published in PLOS Medicine in 2005 provocatively titled “Why Most Published Research Findings Are False” and how they should be applied to our own research.

The meeting will run from 09.30-11.00am. All colleagues and interested parties are welcome to attend.